Keywords

• Top 1 supplier N,N-Diisopropylethylamine 7087-68-5
• N-ethyl-N-isopropylpropan-2-amine
• 2-Propanamine, N-ethyl-N- (1-methylethyl)-

Quick Details

• ProName: N,N-Diisopropylethylamine
• CasNo: 7087-68-5
• Molecular Formula: C8H19N
• Appearance: colorless liquid
• Application: Intermediates
• DeliveryTime: stock
• PackAge: 150kg/drum
• Port: Shanghai
• ProductionCapacity: 100 Metric Ton/Month
• Purity: 99.7%min
• Storage: Store in cool place.
• Transportation: Store the container tightly closed in ...
• LimitNum: 100 Gram
• Moisture Content: 0.1%max
• Impurity: 0.1%max

Superiority

Product Application: N,N-Diisopropylethylamine (CAS: 7087-68-5)

N,N-Diisopropylethylamine (DIPEA) is a versatile organic base commonly used in chemical synthesis and industrial applications. Due to its excellent solubility in organic solvents and its ability to neutralize acids efficiently, DIPEA is a key reagent in various reactions across the pharmaceutical, agrochemical, and specialty chemical industries.

Key Applications:

1. Catalyst in Organic Synthesis
   N,N-Diisopropylethylamine is widely used as a base in organic synthesis, particularly in amine catalysis. It facilitates a range of reactions, including dehydrohalogenation, alkylation, and condensation reactions. It is frequently employed in the preparation of pharmaceutical intermediates, fine chemicals, and agrochemicals.

2. Reagent in Pharmaceutical Synthesis
   DIPEA is commonly used in the synthesis of pharmaceuticals and biologically active compounds. It acts as a deprotonating agent to activate certain molecules, making it an essential tool for creating drug molecules with complex structures. It is frequently involved in the production of alkylating agents, enzyme inhibitors, and antiviral compounds.

3. Catalyst in Peptide Synthesis
   In peptide synthesis, N,N-Diisopropylethylamine is used as a base in the activation of carboxyl groups. It is a common reagent in the production of peptide bonds and in coupling reactions involving protected amino acids, playing a crucial role in the formation of peptides and oligomers used in therapeutic applications.

4. As a Base in Transesterification and Amidation
   DIPEA is also used in transesterification reactions and amidation processes, where it helps facilitate the formation of esters and amides from alcohols and acids. This is particularly important in the production of polymer precursors, bioactive esters, and fine chemicals.

5. As a Solvent or Co-Solvent
   Due to its excellent solvency properties, N,N-Diisopropylethylamine is used in some reactions as a co-solvent in organic synthesis, enhancing the solubility of polar and non-polar substrates.

6. Regeneration of Catalysts
   In certain catalytic processes, DIPEA serves to regenerate catalysts that may have become deactivated during reactions, particularly in transition metal catalysis.

Summary:
N,N-Diisopropylethylamine (CAS: 7087-68-5) is a critical reagent in various synthetic processes, widely used as a base and catalyst in the pharmaceutical, agrochemical, and fine chemical industries. Its applications range from the synthesis of complex molecules and active pharmaceutical ingredients to its use in peptide synthesis and organic reactions, making it indispensable in modern chemical manufacturing.

Details

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